Characterization of surface saccharides in two Corynebacterium diphtheriae strains
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چکیده
منابع مشابه
Isolation and characterization of extragenic suppressor strains of Corynebacterium diphtheriae.
The isolation and characterization of two different nonsense suppressor strains of Corynebacterium diphtheriae C7 sup+(-)tox- are described. Appropriate lysogens of these strains with corynephage beta, carrying known class II tox premature polypeptide chain termination mutations [C7sup-1(betatox-30) and C7sup-2(betatox-45)], each produce a 62,000-dalton polypeptide with nicotinamide adenine din...
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The increasing problems with multidrug resistance in relation to Corynebacterium, including C. diphtheriae, are examples of challenges confronting many countries. For this reason, Brazilian C. diphtheriae strains were evaluated by the E-Test for their susceptibility to nine antibacterial drugs used in therapy. Resistance (MIC < 0.002; 0.38 microg/ml) to penicillin G was found in 14.8% of the st...
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By conducting a molecular characterization of Corynebacterium diphtheriae strains in Australia, we identified novel sequences, nonfunctional toxin genes, and 5 recent cases of toxigenic cutaneous diphtheria. These findings highlight the importance of extrapharyngeal infections for toxin gene-bearing (functional or not) and non-toxin gene-bearing C. diphtheriae strains. Continued surveillance is...
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Iron limitation may cause bacterial pathogens to grow more slowly; however, it may also stimulate these microorganisms to produce greater tissue damage, given that many virulence factors are controlled by the iron supply in the environment. The present study investigated the influence of low iron availability on the expression of proteins and surface sugar residues of two toxigenic strains of C...
متن کاملToxinogeny in Corynebacterium diphtheriae.
In 1951, Freeman made the remarkable discovery that nontoxinogenic Corynebacterium diphtheriae became toxinogenic2 after association with the lytic phage B, previously described by Toshach (1950). From lysates of nontoxinogenic, nonlysogenic C. diphtheriae, Freeman and Morse (1951) established, through the isolation of single cells, lysogenic strains which were toxinogenic. The lysogenic clones...
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ژورنال
عنوان ژورنال: FEMS Microbiology Letters
سال: 1999
ISSN: 0378-1097
DOI: 10.1016/s0378-1097(98)00540-0